Record Details

Barnitt, Jr, Allan E;Goertemiller, Jr, Clarence C
Nasal salt-secreting glands of normal and hyperkalemically stressed Sauromalus obesus: histology and cytology
Journal Article
Sauromalus obesus
Each of the bilateral nasal glands of Sauromalus obesus is composed of a richly vascularized loose connective tissue stroma and a parenchyma of compound branched tubules that radiate from the main excretory duct. The principal secretory portions of these tubules are continuous with short terminal segments. Small round basal cells are randomly interspersed among the light and dark columnar secretory cells of the principal secretory segments. Few basal cells are found in the distal portions of the secretory segments while they are more numerous near the excretory duct. These cells might be undifferentiated epithelial replacement cells that migrate from the collecting ducts and replace degenerating, principal secretory cells. The terminal tubular segments are lined with both granular and agranular cells. The granular cells contain metachromatic cytoplasmic granules along with flattened basal nuclei, and they appear to be similar to mucus secreting cells. In contrast, the agranular cells closely resemble the principal secretory cells. Experimental hyperkalemia induced cellular hypertrophy and a corresponding increase in the diameter of the secretory tubules that apparently displaced the intertubular connective tissue. In addition, peripheral venous sinuses and the vascular elements associated with the principal tubules were especially engorged with blood. These observations suggest an increase in the secretory activity of the principal segments in response to elevated KCI load.