The following conditions are described: granulomatous pseudotumours found in several specimens of Lacerta sicula Raf. and in the iguana Cyclura cornuta Cope; a mesenchymosarcoma found in Lacerta sicula Raf.; an adenocarcinoma and a rhabdomyosarcoma found in a Boa constrictor Laur. An ileal intussusception and a severe lymphocytic (lymphoid) thyroiditis were incidentally found in the Boa constrictor. The conditions are discussed and attention drawn to the differential diagnosis of reptile tumours.